 
Article Date: 16 Jul 2010 – 2:00 PDT
Depression, known to be a condition with impaired psychosocial functioning that severely impacts the quality of life of patients and families, is actually defined with specific clinical symptoms such as sadness, difficulty to experience pleasure, sleep problems etc., present for at least two weeks. At least 40% of depressed patients actually benefit from an antidepressant treatment, whereas 20 – 30% of patients may suffer from chronic depression that negatively impacts their quality of life. In order to improve the efficiency of treatment and reduce the burden of depressive disorders, depression needs to be defined at the neurobiological level.
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