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Article Date: 25 May 2010 – 1:00 PDT

New data presented at the American Psychiatric Association’s annual meeting suggests a benefit to combining L-methylfolate, a prescription medical food called Deplin®, with an antidepressant at the start of treatment. This retrospective analysis showed a significantly greater improvement in depression symptoms in a shorter period of time, when patients with Major Depressive Disorder (MDD) were started on combination therapy. The retrospective study compared patients taking L-methylfolate with either a selective serotonin reuptake inhibitor (SSRI) or a serotonin norepinephrine reuptake inhibitor (SNRI) versus patients who were only prescribed an SSRI or SNRI.

“We know from studies that nearly 70% of depressed individuals will not reach remission by taking one antidepressant alone, so clearly a new approach is needed,” explained the study’s principal investigator, Lawrence D. Ginsberg, M.D. of Red Oak Psychiatry, Houston, Texas. “Adding L-methylfolate to an antidepressant at the start of treatment has valuable benefits for these patients.”

Read in Full:  http://www.medicalnewstoday.com/articles/189730.php



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