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A new study raises serious questions about the increasingly common use of second-generation antidepressant drugs to treat anxiety disorders.
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Although the practice is becoming increasingly common, researchers worry that the value of the drugs for anxiety may have been overestimated as a result of publication bias.
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Publication bias occurs when only studies that show beneficial effects of the intervention are published.
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As reported in JAMA Psychiatry, the new review concludes that studies supporting the value of second-generation antidepressant drugs for the treatment of anxiety have been distorted by publication bias, outcome reporting bias and “spin.â€
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Even though they may still play a role in treating these disorders, the effectiveness of the drugs has been overestimated, say the researchers.
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In some cases the medications, which are among the most widely prescribed drugs in the world, are not significantly more useful than a placebo.
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