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by: K. M. Lampi, A. Sourander, M. Gissler, S. Niemelä, K. Rehnström, E. Pulkkinen, L. Peltonen, L. Von Wendt

 

Acta Pædiatrica, Vol. 99, No. 9. (19 September 2010), pp. 1425-1428. doi:10.1111/j.1651-2227.2010.01835.x Key: citeulike:70962333

Abstract

 

Abstract Aims:  The aim of the study was to explore the validity of registry-based diagnoses of autism in Finland using the Autism Diagnostic Interview – Revised (ADI-R). This study was designed for the Finnish Prenatal Study of Autism and Autism Spectrum Disorders (FIPS-A), an ongoing research project where registry-based diagnoses will be used for epidemiological studies. Methods:  In this small pilot study, a clinical sample of 95 subjects diagnosed with childhood autism or pervasive developmental disorder/pervasive developmental disorder – not otherwise specified (PDD/PDD-NOS) or Asperger′s syndrome according to the Finnish Hospital Discharge Register (FHDR) was gathered nationwide. A small control group consisting of siblings without any registered diagnoses of those being examined was also included in the study. Diagnoses were further re-evaluated by interviewing parents with the ADI-R.

Results:  The mean scores of autistic subjects clearly exceeded cut-off limits for autism on all three ADI-R domains and 96% of the subjects with registered diagnosis of childhood autism fulfilled the criteria based on the instrument as well. Conclusion:  These results suggest that the validity of Finnish registry-based diagnoses of childhood autism can be considered good. Our findings lay important groundwork for further population- based studies of the aetiology of autism.

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